Molecular Medicine Program

This program is led by Andrew Arnold, M.D. There are six doctorally prepared faculty (PhD- or physician-scientists) engaged in human disease-oriented laboratory research in the Center for Molecular Medicine.

Dr. Arnold's laboratory investigates the molecular genetic basis of tumors of the endocrine glands. The cyclin D1 oncogene, initially discovered by Dr. Arnold in parathyroid tumors, has a broad role in human cancer and its action in breast cancer is specifically being investigated. Dr. Arnold's laboratory is also pursuing their recent discovery of the major genetic basis of parathyroid gland cancers.

Dr. Sanjay Mallya collaborates on endocrine tumor work with Dr. Arnold, and also has an independent program investigating the molecular basis of oral cancer.

Dr. Jennifer Tirnauer is uniquely merging her scientific expertise in microtubule and cytoskeletal biology with her commitment to cancer research, and is investigating the role of microtubule defects in the abnormal cellular architecture found in breast and colon cancer, among others.

Dr. Marc Hansen investigates the molecular basis of tumors of bone, including study of a new tumor suppressor gene discovered in his laboratory. Center for Molecular Medicine investigator

Dr. Anne Delany participates in the Bone Program as well, and is investigating the molecular mechanisms by which tumors, particularly prostate cancer, metastasize to bone.

Dr. Daniel Rosenberg is active in colon cancer research, as further described in the Molecular GI Cancer Program.