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Clinical Trials: Prevention and Screening

Prevention Trials

Therapeutic Area: Breast Cancer

Principal Investigator: Dr. Carolyn Runowicz

Title: A phase III randomized study of exemestane vs. placebo in postmenopausal women at increased risk of developing breast cancer

Description: In this trial, a sample of women who are at high-risk for breast cancer randomly will be placed into one of two groups; the group that will receive exemestane or the group that will receive the placebo (sugar pill). Women who participate in this study will need to take one pill a day for the next five years.  Neither the participant nor the doctor/staff will know to which group the individual has been randomly placed. The investigators want to learn if exemestane is effective in preventing breast cancer in women that are at an increased risk of developing the disease.

Length/Duration: 5 years

Compensation: None

Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center

For more information, patient benefits, and to learn if you qualify: please call 860-679-3066 or send an email to dnoel@uchc.edu

IRB #: 06-163

Sponsor: National Cancer Institute of Canada

Principal Investigator: Dr. Carolyn Runowicz

Title: Collection of Clinical Samples from Patients at High Risk for Ovarian Cancer for Biomarker Studies

Description: The purpose of this study to determine the clinical utility of a panel of ovarian cancer markers to screen patients at high-risk for the development of ovarian cancer. This study will examine blood taken from patients with and without ovarian cancer and analyzed for the presence or absence of the identified markers.

Length/Duration: 1 hour

Compensation: None

Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center

For more information, patient benefits, and to learn if you qualify: please call 860-679-3066 or send an email to dnoel@uchc.edu

IRB #: 06-160

Sponsor: Tripath

Screening Trials

Therapeutic Area: Breast Cancer

Principal Investigator: Dr. Scott Kurtzman

Title: Serial Evaluation of Ductal Epithelium (SEDE) and Breast Health Outcomes in Women at High Risk for Breast Cancer

Description: In this trial, a sample of women who are at high-risk for breast cancer and who have no evidence of breast malignancy, will be followed over an approximate five-year period. Subjects will undergo a ductal lavage procedure on a serial basis and overall breast health will be recorded based on physical exam and mammograms.

Length/Duration: 5 years

Compensation: Maximum of $100.00

Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center

For more information, patient benefits, and to learn if you qualify: please call 860-679-3066 or send an email to dnoel@uchc.edu

IRB #: 05-005

Sponsor: Cytyc Corporation

About Clinical Trials

Current Clinical Trials

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