Clinical Trials: Oral Cancer/Head and Neck Carcinomas
Therapeutic Area: Head and Neck
Principal Investigator:
Dr. Upendra Hegde
Title: A randomized phase III trial comparing
sequential therapy with TPF/Chemoradiation (ST) to
cisplatinum-base chemoradiotherapy with accelerated
concomitant boost radiotherpay (CRT) for locally advanced
squamous cell cancer of the head and neck (The Paradigm
study).
Description: This study is for people with
squamous cell carcinoma of the head and neck. The
purpose of this study is to determine if treating these
patients with a combination of docetaxel/cisplatin/5-fluorouracil
for three cycles followed by treatment with additional
chemotherapy and concurrent radiotherapy is more effective
than the standard treatment plan of giving chemotherapy at
the same time as giving radiotherapy.
Length/Duration: Up to 4 months of treatment
followed by up to 5 years of follow-up
Compensation: None
For more information, patient benefits, and to learn if you qualify:
please call 860-679-3066 or send an email to dnoel@uchc.edu
IRB #: 05-236
Sponsor: Dana Farber Cancer Institute
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Research
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