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Clinical Trials: Gastrointestinal Cancer

Treatment Trials

Prostate

Therapeutic Area: Prostate

Principal Investigator: Dr. Susan Tannenbaum

Title: S9921: Adjuvant Androgen Deprivation Versus Mitoxantrone Plus Prednisone Plus Androgen Deprivation in Selected High Risk Prostate Cancer in Patients Following Radical Prostatectomy

Description: The purpose of this study is to determine if patients with high risk localized prostate cancer that have had a prostatectomy will benefit from post-operative treatment with one of the following combinations of drugs: bicalutamide (Casodex) + gosereline acetate (Zoladex) or mitoxantrone + prednisone given with Casodex + Zoladex.

Length/Duration: 24 months of treatment, 15 years of follow-up

Compensation: None

Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center

For more information, patient benefits, and to learn if you qualify: please call 860-679-3066 or send an email to dnoel@uchc.edu

IRB #: 03-212

Sponsor: Eastern Oncology Cooperative Group (ECOG)

Pancreas

Therapeutic Area: Prostate Cancer

Principal Investigator: Dr. Susan Tannenbaum

Title: S9346 Intermittent Androgen Deprivation in Patients with Stage D2 Prostate Cancer

Description: Patients with stage D2 prostate cancer are treated with 8 cycles of Casodex. If PSA levels stabilize, patients are placed on one of two treatment regimens. Patients may be randomized to one of two treatment arms, either continuous treatment with Casodex for an additional 8 cycles, or an intermittent treatment with Casodex over the same time period.

Length/Duration: Minimum of 8 months treatment, additional treatment depends on response

Compensation: None

Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center

For more information, patient benefits, and to learn if you qualify: please call 860-679-3066 or send an email to dnoel@uchc.edu

IRB #: 96-212

Sponsor: Eastern Oncology Cooperative Group (ECOG)

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