Clinical Trials: Colorectal Cancer
Therapeutic Area: Cancer of the Rectum
Principal Investigator: Dr. Scott Kurtzman
Title: NSABP R04: A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with Preoperative Radiation Therapy and Continuous IV Infusion (CVI) of 5-FU
in the Treatment of Patients with Operable Carcinoma of the Rectum
Description: The purpose of this study is to compare the rate of local-regional relapse in patients receiving preoperative oral capecitabine with radiotherapy (XRT) to
that in patients receiving preoperative continuous intravenous infusion (CVI) 5-FU + XRT.
Length/Duration: Treatment 5 to 6 weeks, follow-up for 5 years
Compensation: None
Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center
For more information, patient benefits, and to learn if you qualify:
please call 860-679-3066 or send an email to dnoel@uchc.edu
IRB #: 05-061
Sponsor: National Surgical Breast and Bowl Project (NSABP)
 Therapeutic Area: Colon
Principal Investigator: Dr. Scott Kurtzman
Title: NSABP C08: Clinical Trial Comparing Infusional 5-FU, Leucovorin, and Oxaliplatin (mFOLFOX6) Every Two Weeks With Bevacizumab to the Same Regimen Without
Bevacizumab for the Treatment of Patients With Resected Stages II And III Carcinoma of the Colon
Description: This phase III study will evaluate the relative efficacy of infusional 5-fluorouracil (5-FU), leucovorin (LV), and oxaliplatin (mFOLFOX6) alone or the same
chemotherapy regimen plus bevacizumab in patients with resected stages II and III carcinoma of the colon. The primary goal of the study is to determine whether disease-free
survival (DFS) can be improved by the addition of bevacizumab to oxaliplatin. Other goals are to compare the relative efficacy of the two regimens in prolonging survival and to
evaluate adverse events related to bevacizumab.
Length/Duration: Treatment 6 months, follow-up 5 years
Compensation: None
Location: Neag Comprehensive Cancer Center at the University of Connecticut Health Center
For more information, patient benefits, and to learn if you qualify:
please call 860-679-3066 or send an email to dnoel@uchc.edu
IRB #: 05-084
Sponsor: National Surgical Breast and Bowl Project (NSABP) |
Research
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